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연구업적및저서

Lim JS, et al., Mucosal TLR5 activation controls healthspan and longevity. Nature Communications. 2020. Under revision

Lim JS, et al., Identification of a novel senomorphic agent, avenanthramide C, via the suppression of the senescence-associated secretory phenotype. Mech ageing dev. Mechanisms of Ageing and Development. 2020 Under revision

Lee DY, et al., Differential Activation of Macrophages based on their Environment in Advanced Age. Chonnam Med J. 2020. Jan;56(1):12-19


Kuk MU, et al., Alleviation of Senescence via ATM Inhibition in Accelerated Aging Models. Mol Cells. 2019 Mar
31;42(3):210-217.

Yoon G, et al., Transcriptomic Analysis of High Fat Diet Fed Mouse Brain Cortex. Front Genet. 2019 Feb 19;10:83.

Sueoka E, et al., Meeting report of the 14th Japan-Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine. J Cancer Res Clin Oncol. 2019 May;145(5):1263-1271.

Park JT, et al., A crucial role of ROCK for alleviation of senescence-associated phenotype. Exp Gerontol. 2018 Jun;106:8-15.

Sohn EJ, et al., Restoring Effects of Natural Anti-Oxidant Quercetin on Cellular Senescent Human
Dermal Fibroblasts. Am J Chin Med. 2018;46(4):853-873.

Park JT, et al., Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence. Ageing Res Rev. 2018 Nov;47:176-182.

Nguyen KC, Cho KA. Versatile Functions of Caveolin-1 in Aging-related Diseases. Chonnam Med J. 2017 Jan;53(1):28-36.

Lim JS, et al., The role of TLR9 in stress-dependent autophagy formation. Biochem Biophys Res Commun. 2016 Dec 9;481(3-4):219-226.


Lim JS, Kim HS, Nguyen KC, Cho KA. The role of TLR9 in stress-dependent autophagy formation. Accepted in Biochem Biophys Res Commun. 2016.

Ahn SH, Cho SH, Song JE, Kim S, Oh SS, Jung S, Cho KA, Lee TH. Caveolin-1 serves as a negative effector in senescent human gingival fibroblasts during Fusobacterium nucleatum infection. Mol Oral Microbiol. 2016 Jun 17. doi: 10.1111/omi.12167. [Epub ahead of print]

Choi KH, Kim HS, Park MS, Kim JT, Kim JH, Cho KA, Lee MC, Lee HJ, Cho KH. Regulation of Caveolin-1 Expression Determines Early Brain Edema After Experimental Focal Cerebral Ischemia. Stroke. 2016 May;47(5):1336-43.

Lim JS, Nguyen KC, Han JM, Jang IS, Fabian C, Cho KA. Direct Regulation of TLR5 Expression by Caveolin-1. Mol Cells. 2015 Nov 26. doi: 10.14348/molcells.2015.0213. [Epub ahead of print]

Lim JS, Chung NE, Jang IK, Lee SE, Rhee JH, Cho KA. Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence.. Aging Cell. (JCR Top 2 %).2015 Oct;14(5):907-15

Lee JA, Choi DI, Choi JY, Kim SO, Cho KA, Lee JB, Yun SJ, Lee SC. Methyl-ββ-cyclodextrin up-regulates collagen I expression in chronologically-aged skin via its anti-caveolin-1 activity. Oncotarget (JCR Top 10 %). 2015 Feb 10;6(4):1942-53

Lim JS, Shin M, Kim HJ, Kim KS, Choy HE, Cho KA. Caveolin-1 mediates Salmonella invasion via regulation of SopE dependent Rac1 activation with actin reorganization. J Infect Dis (JCR Top 10 %). 2014 Sep 1;210(5):793-802.

Nguyen KC, Muthiah M, Islam MA, Kalash RS, Cho CS, Park H, Lee IK, Kim HJ, *Park IK, *Cho KA. Selective transfection with osmotically active sorbitol modified PEI nanoparticles for enhanced anti-cancer gene therapy. Colloids Surf B Biointerfaces. 2014 Jul 1;119:126-36

Kim SO, Song SH, Lee SC, Cho KA, Park JS, Kwon D, Park K.Altered expression of caveolin-1 and -3 in smooth muscle of rat urinary bladder by 17-extradiol. BMC Urol. 2013 Sep 16;13:44

[특허]
2019.09: 패혈증 비브리오균의 편모 구성성분인 플라젤린과 병원체의 항원 단백을 융합시킨 재조합 단백을 포함하는 노화예방 개선 또는 치료용 조성물(골다공증 효과에 대한 분할특허). 등록국가: 미국, 등록번호: 10,407,471

2017.06: 패혈증 비브리오균의 편모 구성성분인 플라젤린과 병원체의 항원 단백을 융합시킨 재조합 단백을 포함하는 노화예방 개선 또는 치료용 조성물(비만예방 효과에 대한 분할특허). 등록국가: 대한민국, 등록번호: 10-1749317

2017.06: 패혈증 비브리오균의 편모 구성성분인 플라젤린과 병원체의 항원 단백을 융합시킨 재조합 단백을 포함하는 노화예방 개선 또는 치료용 조성물(노화관련탈모개선효과에 대한 분할특허) 등록국가: 대한민국, 등록번호: 10-1749318

2016.05: PspA를 유효성분으로 포함하는 퇴행성 뇌질환의 예방 또는 치료용 약학 조성물 등록국가: 대한민국, 등록번호: 10-1627285

201505: 패혈증 비브리오균의 편모 구성성분인 플라젤린과 병원체의 항원 단백을 융합시킨 재조합 단백을 포함하는 노화 예방, 개선 또는 치료용 조성물(노화관련 백내장, 탈장, 골다공증등의 다각적 항노화 효과의 특허) 등록국가: 대한민국, 등록번호: 10-1520336

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