Basic Medical Science

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  • In-Kyu Park교수님 사진
  • In-Kyu Park

    Departmant  Biomedical Sciences
    Major  His research focuses on nanoparticlesmediated delivery of therapeutic drug and genes. The fate of those particles inbody can be monitored non-invasively by MRI and optical imaging after labellingthem with the appropriate imaging agents. Bio-compatible hyd
    E-mail  pik96@jnu.ac.kr Homepage  

Research

1. Woo Kyun Bae, Myong Suk Park, Ji Hee Lee, Jun Eul Hwang, Hyun Jeong Shim, Sang HeeCho, Dae-Eun Kim, Hyang Mi Ko, Chong-Su Cho, In-Kyu Park*, Ik-Joo Chung*, Docetaxelloaded thermo-responsive conjugated linoleic acid-incorporated poloxamerhydrogel for the suppression of peritoneal metastasis of gastric cancer,Biomaterials, 34 (4) 1433-1441 (2013) (IF: 7.404 as of 2011).
2. Muthunarayanan Muthiah, Hieu Vu-Quang, You-Kyoung Kim, Joon Haeng Rhee, Sang Hyeon Kang, SooYoun Jun, Yun-Jaie Choi, Yong Yeon Jeong, Chong-Su Cho*, In-Kyu Park*, Mannose-poly(ethyleneglycol)-linked SPION targeted to antigen presenting cells for magneticresonance imaging on lymph node, Carbohydrate Polymers, 92 (2) 1586-1595 (2013)(IF: 3.628 as of 2011).92,
3. M. Muthiah, Sang Joon Lee, Myeongju Moon, Hyun Jin Lee, Woo Kyun Bae, Ik JooChung, Yong Yeon Jeong, In-Kyu Park*,Surface tunable polymersomes loaded with magnetic contrast agent and drug forimage-guided cancer therapy, Journal of Nanoscience and Nanotechnology, 13 (3)1626-1630 (2013) (IF: 1.563 as of 2011).
4. Reju Thomas, In-Kyu Park, YongYeon Jeong, Magnetic Iron Oxide Nanoparticles for Multimodal Imaging andTherapy of Cancer, Int. J. Mol. Sci. 14 (8) 15910-15930 (2013) (IF: 2.464 as of2012).
5. Muthunarayanan Muthiah, In-Kyu Park*,Chong-Su Cho, Nanoparticle-mediated delivery of therapeutic genes: focus on miRNAtherapeutics, Expert Opin. Drug Deliv. 10 (9) 1259-1273 (2013) (IF: 4.869 as of2012).
6. Sewook Oh, Minkeun Kim, Yejin Kim, Hunsang Jung, Tae-Sik Yoon, Young-Jin Choi, ChiJung Kang, Myeong-Ju Moon, Yong-Yeon Jeong, In-Kyu Park, Hyun Ho Lee, Organic memory device withself-assembly monolayered aptamer conjugated nanoparticles, Applied PhysicsLetters 103 (8) 083702 (2013) (IF: 3.794 as of 2012).
7. In Hee Shin, Seok Ki Kim, Ju Beom Eom, Jae Seok Park, Hyeong Ju Park, In-Kyu Park, Byeong-il Lee, Novelimaging system for positioning of the indocyanine green (ICG) target; visibleprojection of the near-infrared fluorescence image, Journal of BiomedicalScience and Engineering, 6 (9) 898-900 (2013).
8. Neethu Ninan, Muthunarayanan Muthiah, In-KyuPark, Anne Elain, Sabu Thomas, Yves Grohens, Pectin/Carboxymethylcellulose/ Microfibrillated cellulose composite scaffolds for tissueengineering, Carbohydrate Polymers, 98 (1) 877-885 (2013) (IF: 3.479as of 2012).
9. Neethu Ninan, Muthunarayanan Muthiah, In-KyuPark, Anne Elain, Sabu Thomas, Yves Grohens, Faujasites incorporatedtissue engineering scaffolds for wound healing: In vitro and In vivo analysis, ACSApplied Materials &Interfaces, 5 (21) 11194-11206 (2013) (IF: 5.008 as of2012).
10. Muthunarayanan Muthiah, In-Kyu Park*,Chong-Su Cho*, Surface modification of iron oxide nanoparticles bybiocompatible polymers for tissue imaging and targeting, BiotechnologyAdvances, 31 (8) 1224-1236 (2013) (IF: 9.599 as of 2012).
11. Han Shanhua, Han Huijing, Myeong Ju Moon, Suk Hee Heo, Hyo Soon Lim, In-Kyu Park, Chong-Su Cho, SangHyun Kwak, Yong Yeon Jeong, MR Detection of LPS-Induced Neutrophil Activationusing Mannan-Coated Superparamagnetic Iron Oxide Nanoparticles, Mol. ImagingBiol. 15 (6) 685-692 (2013) (IF: 3.095 as of 2011).
12. Hwa Jeong Lee, Ran Namgung, Won Jong Kim, Jae Il Kim, In-Kyu Park*, Targeted Delivery of MicroRNA-145to Metastatic Breast Cancer by Peptide Conjugated Branched PEI Gene Carrier, MacromolecularResearch, 21(11) 1201-1209 (2013) (IF: 1.639 as of 2012)
13. Muthunarayanan Muthiah, Mohammed Ariful Islam, Chong-Su Cho, Jun Eul Hwang, Ik-Joo Chung, In-Kyu Park*, Substrate-mediateddelivery of microRNA-145 through a polysorbitol-based osmotically activetransporter suppresses smooth muscle cell proliferation: implications forrestenosis treatment, Journal of Biomedical Nanotechnology, 10 (4) 571-579 (2014)(IF: 5.256 as of 2012).
14. You-Kyoung Kim, Bijay Singh, Hu-Lin Jiang, Tae-Eun Park, Tao Jiang, In-Kyu Park, Myung-Haing Cho,Sang-Kee Kang, Yun-Jaie Choi, Chong-Su Cho, N-acetylglucosamine-conjugatedblock copolymer consisting of poly(ethylene oxide) and cationic polyaspartamideas a gene carrier for targeting vimentin-expressing cells, European Journal of Pharmaceutical Sciences 51:165-172 (2014) (IF: 2.987 as of 2012).
15. Neethu Ninan, Muthunarayanan Muthiah, Nur Aliza Bt.Yahaya, In-Kyu Park, Anne Elain, Tin Wui Wong, Sabu Thomas, YvesGrohens, Antibacterial and wound healing analysis of Gelatin/Zeolite scaffolds,Colloids and Surfaces B: Biointerfaces, 115: 244-252 (2014) (IF: 3.554 as of 2012).
16. Muthunarayanan Muthiah, Seung-Hwan Park, Md Nurunnabi, Jooyoung Lee, Yong-kyu Lee, HansooPark, Byeong-il Lee, Jung-Joon Min, In-KyuPark*, Intracellular delivery and activation of geneticallyencoded photosensitizer Killer Red by Quantum Dots encapsulated in polymericmicelles, Colloids and Surfaces B: Biointerfaces, 116, 284-294 (2014) (IF: 3.554as of 2013).
17. Bijay Singh, Yun-Jaie Choi, In-Kyu Park,Toshihiro Akaike, Chong-Su Cho, Chemical Modification of Chitosan withpH-Sensitive Molecules and Specific Ligands for Efficient DNA Transfection and siRNA Silencing, J. Nanosci. Nanotechnol. 14 (1) 564-576 (2014) (IF: 1.149 asof 2013).
18. Saji Uthaman, S. Maya, R. Jayakumar, Chong-Su Cho, In-Kyu Park*, Carbohydrate-Based Nanogels as Drugand Gene Delivery Systems, J. Nanosci. Nanotechnol. 14 (1) 694-704 (2014) (IF: 1.149as of 2013).
19. Kim Cuc Thi Nguyen, Muthunarayanan Muthiah, Mohammad Ariful Islam, R Santhosh Kalash, Chong-Su Cho, Hansoo Park, Il-Kwon Lee, Hyeoung-Joon Kim, In-Kyu Park*, Kyung A Cho, Selective transfectionwith osmotically active sorbitol modified PEI nanoparticles for enhanced anti-cancer gene therapy, Colloids and Surfaces B: Biointerfaces, 119, 126-136(2014) (IF: 3.554 as of 2013).
20. Dool-Ri Oh, Hu Won Kang, Jong-Ro Kim, Sunoh Kim, In-Kyu Park, Joon Haeng Rhee,Won Keun Oh, and Young Ran Kim, PMA Induces Vaccine Adjuvant Activity by theModulation of TLR Signaling Pathway, Mediators of Inflammation, 2014 (ID406514) 1-8 (IF: 3.236 as of 2014).
21. Renjith P. Johnson, Saji Uthaman, Johnson V. John, Min Seon Heo, In Kyu Park, Hongsuk Suh, Il Kim, Poly(2-Hydroxyethyl Methacrylate)-b-Poly(L-Lysine) Cationic Hybrid Materialsfor Non-Viral Gene Delivery in NIH 3T3 Mouse Embryonic Fibroblasts, Macromol.Biosci. 14(9) 1239-1248 (2014) (IF: 3.554 as of 2013).
22. Neethu Ninan, Muthunarayanan Muthiah, In-Kyu Park, Nandakumar Kalarikkal, Anne Elain, Tin Wui Wong, Sabu Thomas,Yves Grohens, Wound healing analysis of pectin/ carboxymethyl cellulose/microfibrillated cellulose based composite scaffolds, Materials Letters, 132,34-37 (2014) (IF: 2.224 as of 2013).
23. Sanoj Rejinold N, Reju George Thomas, Muthunarayanan Muthiah, Krishna PrasadChennazhi, In-Kyu Park*, Yong Yeon Jeong, Manzoor Koyakutty, Jayakumar Rangasamy*, Radiofrequency triggered curcumin delivery from thermo and pH responsivenanoparticles containing gold nanoparticles and its in vivo localizationstudies in orthotopic breast tumor model, RSC Advances, 4: 39408-39427 (2014)(IF: 3.708 as of 2013).
24. Muthunarayanan Muthiah, Mohammad Ariful Islam, Hwa-Jeong Lee, Myoeng-Ju Moon,Chong-Su Cho, In-Kyu Park*, MicroRNA delivery with osmotic polysorbitol-based transporter suppresses breastcancer cell proliferation, International Journal of Biological Macromolecules, 72,1237-1243 (2015) (IF: 3.096 as of 2013)
25. N. Sanoj Rejinold, Reju George Thomas, Muthunarayanan Muthiah, K.P. Chennazhi, K.Manzoor, In-Kyu Park*, Yong Yeon Jeong, R. Jayakumar*, Anti-cancer, pharmacokinetics andtumor localization studies of pH-, RF-and thermo-responsive nanoparticles, InternationalJournal of Biological Macromolecules, 74, 249-262 (2015) (IF: 3.096 as of 2013)
26. Muthunarayanan Muthiah, Hui-Lian Che, Santhosh Kalash, Jihoon Jo, Seok-Yong Choi, Won JongKim, Chong Su Cho, Jae Young Lee, In-KyuPark*, Formulation of Glutathione responsiveanti-proliferative nanoparticles from thiolated Akt1 siRNA and disulfide-crosslinkedPEI for efficient anti-cancer gene therapy, Colloids and Surfaces B:Biointerfaces, 126, 322-327 (2015) (IF: 4.287 as of 2013).
27. Sang Joon Lee, Mi-Sun Kang, Jong-Suk Oh, Young-Il Jeong, In-Kyu Park, Hyun Chul Lee, Nano-Aggregates ofDoxorubicin-Conjugated Methoxy Poly(ethylene glycol)-b-Carboxymethyl Dextran Copolymer, Journal of Nanoscience and Nanotechnology, 15 (8) 5566-5570 (2015)(IF: 1.339 as of 2013).
28. Sang Joon Lee, Yong-Ho Shim, Jong-Suk Oh, Young-Il Jeong, In-Kyu Park*, Hyun Chul Lee, Folic acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymernanoparticles for folate receptor-mediated drug delivery, Nanoscale Research Letters, 10 (1) 43 (2015) (IF: 2.48 as of 2013).
29. Sung Jun Park, Yu Kyung Lee, Sunghoon Cho, Saji Uthaman, In-Kyu Park, Jung-Joon Min, Seong Young Ko, Jong-Oh Park andSukho Park, Effect of Chitosan Coating on a Bacteria-based Alginate Microrobot,Biotechnology and Bioengineering, 112 (4) 769-776 (2015) (IF: 4.164 as of 2013)
30. Saji Uthaman, Sang Joon Lee, Kondareddy Cherukula, In-Kyu Park*, Chong Su Cho, Polysaccharide-coatedmagnetic nanoparticles for imaging and gene therapy, BioMed Research International, 2015 ID: 959175, 1-14 (2015) (IF: 2.706 as of 2013)
31. Neethu Ninan, Muthunarayanan Muthiah, In-Kyu Park, Anne Elain, Tin Wui Wong, Sabu Thomas, Yves Grohens, In vitro and in vivo evaluation of pectin/copper exchanged faujasite composite membranes, Journal of Biomedical Nanotechnology, 11 (9) 1550-1567 (2015) (IF: 7.578 as of 2013).
32. Neethu Ninan Muthunarayanan Muthiah, In-Kyu Park, Anne Elain, Tin Wui Wong, Sabu Thomas, Yves Grohens, Natural Polymer/Inorganic material based hybrid scaffolds for skin wound healing, Polymer Reviews, 55, 1-38 (2015) (IF: 6.593 as of 2013).
33. Hwa-Jeong Lee, Sang Joon Lee, Saji Uthaman, Reju George Thomas, Hoon Hyun, Yong Yeon Jeong, Chong-Su Cho, In-Kyu Park*, Biomedical Applications of Magnetically Functionalized Organic/Inorganic Hybrid Nanofibers, Int. J. Mol. Sci. 16 (6) 13661-13677 (2015) (IF: 2.862 as of 2014)
34. My-Dung Hoang, Hwa-Jeong Lee, Hyun-Ju Lee, Sung-Hoon Jung, Nu-Ri Choi, Manh-Cuong Vo, Thanh-Nhan Nguyen-Pham, Hyeoung Joon Kim, In-Kyu Park, Je Jung Lee, Branched polyethylenimine-superparamagnetic ironoxide nanoparticles (bPEI-SPIONs) improve the immunogenicity of tumor antigens and enhance Th1 polarization of dendritic cells, Journal of Immunology Research, 2015: ID 706379, 1-9 (2015) (IF: 2.934 as of 2013).
35. Reju George Thomas, Myeong Ju Moon, Hyegyeong Lee, Arathyram Ramachandra Kurup Sasikala, Cheol Sang Kim, In-Kyu Park, Yong Yeon Jeong, Hyaluronic acid conjugated superparamagnetic iron oxide nanoparticle for cancer diagnosis and hyperthermia therapy, Carbohydrate Polymers 131, 439-446 (2015) (IF: 4.074 as of 2014).
36. Hui-Lian Che, Hwa Jeong Lee, Koichiro Uto, Mitsuhiro Ebara, Won Jong Kim, Takao Aoyagi, In-Kyu Park*, Simultaneous drug and gene delivery from the biodegradable poly (ε-caprolactone) nanofibers for the treatment of liver cancer, Journal of Nanoscience and Nanotechnology, 15 (10) 7971-7975 (2015) (IF: 1.556 as of 2014).
37. Saji Uthaman, Myeong Ju Moon, Duhwan Lee, Won Jong Kim, In-Kyu Park*, Di-sulfide linked Polyethylenimine coated Gold Nanoparticles as a Non-viral Gene Delivery Agent in NIH-3T3 Mouse Embryonic Fibroblast, Journal of Nanoscience and Nanotechnology, 15 (10) 7895-7899 (2015) (IF: 1.556 as of 2014).
38. Mohammad Ariful Islam, Tae-Eun Park, Emma Reesor, Kondareddy Cherukula, Anwarul Hasan, Jannatul Firdous, Bijay Singh, Sang-Kee Kang, Yun-Jaie Choi, In-Kyu Park*, Chong-Su Cho, Mucoadhesive Chitosan Derivatives as Novel Drug Carriers, Current Pharmaceutical Design, 21(29) 4285-4309 (2015) (IF: 3.452 as of 2014).
39. Renjith P. Johnson, Saji Uthaman, Johnson V. John, Hye Ri Lee, Sang Joon Lee, Huiju Park, In-Kyu Park*, Hongsuk Suh, and Il Kim, Poly(PEGA)-b-poly(l-lysine)-b-poly(l-histidine) Hybrid Vesicles for Tumoral pH-Triggered Intracellular Delivery of Doxorubicin Hydrochloride, ACS Applied Materials &Interfaces, 7(39) 21770-21779 (2015) (IF: 6.723 as of 2014).
40. Hui-Lian Che, In-Ho Bae, Kyung Seob Lim, Saji Uthaman, In Taek Song, HaeshinLee, Duhwan Lee, Won Jong Kim, Youngkeun Ahn, In-Kyu Park*, Myung-Ho Jeong, Novel fabrication of microRNA nanoparticles-coated coronary stent for prevention of post-angioplasty restenosis, Korean Circulation Journal, 46 (1) 23-32 (2016) (IF: 0.753 as of 2014).
41. N. Sanoj Rejinold, Reju George Thomas, Muthunarayanan Muthiah, Hwa-Jeong Lee, Yong Yeon Jeong, In-Kyu Park*, and R. Jayakumar*, Breast Tumor Targetable Fe3O4Embedded Thermo-responsive Nanoparticles for Radiofrequency Assisted Drug Delivery, Journal of Biomedical Nanotechnology, 12(1) 43-55 (2016) (IF: 5.338as of 2014).
42. Saji Uthaman, Shaohui Zheng, Jiwon Han, Young Jin Choi, Sunghoon Cho, Van Du Nguyen,Jong-Oh Park, Seung-Hwan Park, Jung-Joon Min, Sukho Park, In-Kyu Park*, Preparation of Engineered Salmonella Typhimurium-driven Hyaluronic Acid-based Microbeads with bothChemotactic and Biological Targeting towards Breast Cancer Cells for Enhanced Anti-cancer Therapy, Advanced Healthcare Materials, 5 (2) 288-295 (2016) (IF: 5.797as of 2014).
43. SheeEun Lee, Seol Hee Hong, Vivek Verma, Youn Suhk Lee, Tra-My Nu Duong, Kwangjoon Jeong, Saji Uthaman, Young Chul Sung, Jae-Tae Lee, In-Kyu Park, Jung-Joon Min, Joon Haeng Rhee, Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer, OncoImmunology, 5 (2) e1081328 (2016) (IF: 6.266 as of 2014).
44. Kondareddy Cherukula, Kamali Manickavasagam Lekshmi, Saji Uthaman, Kihyun Cho, Chong-Su Cho*, In-Kyu Park*, Multifunctional Inorganic Nanoparticles: Recent Progress in Thermal Therapy and Imaging, Nanomaterials, 6 (4) 76 (2016) (IF: 1.644 as of 2014).
45. Saji Uthaman, Joon-suk Bom, Hyeon Sik Kim, Johnson V. John, Jung-Joon Min, Il Kim, In-Kyu Park*, Tumor homing indocyanine green encapsulated micelles for near infrared and photoacoustic imaging of tumors, Journal of Biomedical Materials Research: Part B – Applied Biomaterials, 104 (4) 825-834 (2016) (IF: 2.759 as of 2014).
46. Md Nurunnabi, MD Nafiujjaman, Sang-Joon Lee, In-Kyu Park, Kang Moo Huh, Yong-kyu Lee, Preparation and characterization of ultra-thin hexagonal boron nitride nanosheets for cancer cell imaging and neurotransmitter sensing, Chemical Communications, 52, 6146-6149 (2016) (IF: 6.834as of 2014).
47. Hui-Lian Che, In-Ho Bae, Kyung Seob Lim, In Taek Song, Haeshin Lee, Duhwan Lee,Won Jong Kim, Myung-Ho Jeong, In-Kyu Park*, Youngkeun Ahn, Therapeutic effect of Akt1 siRNA Nanoparticle Eluting Coronary Stent on Suppression of Post-angioplasty Restenosis, Journal of Biomedical Nanotechnology, 12 (6) 1211-1222 (2016) (IF: 5.338as of 2014).
48. Jisang Yoo, Dae Yong Lee, Vipul Gujrati, N. Sanoj Rejinold, Kamali Manickavasagam Lekshmi, Saji Uthaman, Chanuk Jeong, In-Kyu Park, Sangyong Jon, Yeu-Chun Kim, Bioreducible branched poly(modifiednona-arginine) cell-penetrating peptide as a novel gene delivery platform, Journal of Controlled Release, in press (2016) (IF: 7.441 as of 2014).

Etc